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High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion
DNA methylation is a major regulatory process of gene transcription, and aberrant DNA methylation is associated with various diseases including cancer. Many compounds have been reported to modify DNA methylation states. Despite increasing interest in the clinical application of drugs with epigenetic...
Autores principales: | Shiratori, Hiromi, Feinweber, Carmen, Knothe, Claudia, Lötsch, Jörn, Thomas, Dominique, Geisslinger, Gerd, Parnham, Michael J., Resch, Eduard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066982/ https://www.ncbi.nlm.nih.gov/pubmed/27749902 http://dx.doi.org/10.1371/journal.pone.0163184 |
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