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Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin complex 1 (mTORC1). Transporters have emerged as important amino acid sensors controlling mTOR recruitment and activation at the surface of multiple intracellular compartments...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067300/ https://www.ncbi.nlm.nih.gov/pubmed/27076075 http://dx.doi.org/10.1016/j.cmet.2016.03.013 |