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Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot

Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin complex 1 (mTORC1). Transporters have emerged as important amino acid sensors controlling mTOR recruitment and activation at the surface of multiple intracellular compartments...

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Detalles Bibliográficos
Autores principales:	Goberdhan, Deborah C.I., Wilson, Clive, Harris, Adrian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067300/ https://www.ncbi.nlm.nih.gov/pubmed/27076075 http://dx.doi.org/10.1016/j.cmet.2016.03.013

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