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microRNA-20a Inhibits Autophagic Process by Targeting ATG7 and ATG16L1 and Favors Mycobacterial Survival in Macrophage Cells

Autophagy plays important roles in the host immune response against mycobacterial infection. Mycobacterium tuberculosis (M. tuberculosis) can live in macrophages owing to its ability to evade attacks by regulating autophagic response. MicroRNAs (miRNAs) are small noncoding, endogenously encoded RNA...

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Detalles Bibliográficos
Autores principales: Guo, Le, Zhao, Jin, Qu, Yuliang, Yin, Runting, Gao, Qian, Ding, Shuqin, Zhang, Ying, Wei, Jun, Xu, Guangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067373/
https://www.ncbi.nlm.nih.gov/pubmed/27803889
http://dx.doi.org/10.3389/fcimb.2016.00134