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Decreased expression of Klotho in cardiac atria biopsy samples from patients at higher risk of atherosclerotic cardiovascular disease

BACKGROUND: Klotho proteins (α- and β) are membrane-based circulating proteins that regulate cell metabolism, as well as the lifespan modulating activity of Fibroblast Growth Factors (FGFs). Recent data has shown that higher plasma circulating Klotho levels reduce cardiovascular risk, suggesting Klo...

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Detalles Bibliográficos
Autores principales: Corsetti, Giovanni, Pasini, Evasio, Scarabelli, Tiziano M, Romano, Claudia, Agrawal, Pratik R, Chen-Scarabelli, Carol, Knight, Richard, Saravolatz, Louis, Narula, Jagat, Ferrari-Vivaldi, Mario, Flati, Vincenzo, Assanelli, Deodato, Dioguardi, Francesco S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067432/
https://www.ncbi.nlm.nih.gov/pubmed/27781061
http://dx.doi.org/10.11909/j.issn.1671-5411.2016.08.009