Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes

Protein interactions play significant roles in complex diseases. We analyzed peripheral blood mononuclear cells (PBMC) transcriptome using a multi-method strategy. We constructed a tissue-specific interactome (T2Di) and identified 420 molecular signatures associated with T2D-related comorbidity and...

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Detalles Bibliográficos
Autores principales: Li, Jing-Woei, Lee, Heung-Man, Wang, Ying, Tong, Amy Hin-Yan, Yip, Kevin Y., Tsui, Stephen Kwok-Wing, Lok, Si, Ozaki, Risa, Luk, Andrea O, Kong, Alice P. S., So, Wing-Yee, Ma, Ronald C. W., Chan, Juliana C. N., Chan, Ting-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067504/
https://www.ncbi.nlm.nih.gov/pubmed/27752041
http://dx.doi.org/10.1038/srep35228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067504/
https://www.ncbi.nlm.nih.gov/pubmed/27752041
http://dx.doi.org/10.1038/srep35228

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