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DNA damage precedes apoptosis during the regression of the interdigital tissue in vertebrate embryos
DNA damage independent of caspase activation accompanies programmed cell death in different vertebrate embryonic organs. We analyzed the significance of DNA damage during the regression of the interdigital tissue, which sculpts the digits in the embryonic limb. Interdigit remodeling involves oxidati...
Autores principales: | Montero, Juan A., Sanchez-Fernandez, Cristina, Lorda-Diez, Carlos I., Garcia-Porrero, Juan A., Hurle, Juan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067507/ https://www.ncbi.nlm.nih.gov/pubmed/27752097 http://dx.doi.org/10.1038/srep35478 |
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