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Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1

Human induced pluripotent stem cells (iPSCs) can provide a promising source of midbrain dopaminergic (mDA) neurons for cell replacement therapy for Parkinson's disease (PD). However, iPSC-derived donor cells inevitably contain tumorigenic or inappropriate cells. To eliminate these unwanted cell...

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Detalles Bibliográficos
Autores principales: Samata, Bumpei, Doi, Daisuke, Nishimura, Kaneyasu, Kikuchi, Tetsuhiro, Watanabe, Akira, Sakamoto, Yoshimasa, Kakuta, Jungo, Ono, Yuichi, Takahashi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067526/
https://www.ncbi.nlm.nih.gov/pubmed/27739432
http://dx.doi.org/10.1038/ncomms13097