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Drug Repurposing: Tolfenamic Acid Inactivates PrbP, a Transcriptional Accessory Protein in Liberibacter asiaticus

CLIBASIA_01510, PrbP, is a predicted RNA polymerase binding protein in Liberibacter asiaticus. PrbP was found to regulate expression of a small subset of ribosomal genes through interactions with the β-subunit of the RNA polymerase and a short, specific sequence on the promoter region. Molecular scr...

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Detalles Bibliográficos
Autores principales: Gardner, Christopher L., Pagliai, Fernando A., Pan, Lei, Bojilova, Lora, Torino, Maria I., Lorca, Graciela L., Gonzalez, Claudio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067538/
https://www.ncbi.nlm.nih.gov/pubmed/27803694
http://dx.doi.org/10.3389/fmicb.2016.01630