Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia

Diurnal variations in pain hypersensitivity are common in chronic pain disorders, but the underlying mechanisms are enigmatic. Here, we report that mechanical pain hypersensitivity in sciatic nerve-injured mice shows pronounced diurnal alterations, which critically depend on diurnal variations in gl...

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Detalles Bibliográficos
Autores principales: Koyanagi, Satoru, Kusunose, Naoki, Taniguchi, Marie, Akamine, Takahiro, Kanado, Yuki, Ozono, Yui, Masuda, Takahiro, Kohro, Yuta, Matsunaga, Naoya, Tsuda, Makoto, Salter, Michael W., Inoue, Kazuhide, Ohdo, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067584/
https://www.ncbi.nlm.nih.gov/pubmed/27739425
http://dx.doi.org/10.1038/ncomms13102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067584/
https://www.ncbi.nlm.nih.gov/pubmed/27739425
http://dx.doi.org/10.1038/ncomms13102

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