LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis

Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease for which there are no effective therapies. Patients with AH show impaired hepatocyte proliferation, expansion of inefficient ductular cells and high lipopolysaccharide (LPS) levels. It is unknown whether LPS mediates ductul...

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Detalles Bibliográficos
Autores principales: Odena, Gemma, Chen, Jiegen, Lozano, Juan Jose, Altamirano, Jose, Rodrigo-Torres, Daniel, Affo, Silvia, Morales-Ibanez, Oriol, Matsushita, Hiroshi, Zou, Jian, Dumitru, Raluca, Caballeria, Juan, Gines, Pere, Arroyo, Vicente, You, Min, Rautou, Pierre-Emmanuel, Valla, Dominique, Crews, Fulton, Seki, Ekihiro, Sancho-Bru, Pau, Bataller, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067590/
https://www.ncbi.nlm.nih.gov/pubmed/27752144
http://dx.doi.org/10.1038/srep35610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067590/
https://www.ncbi.nlm.nih.gov/pubmed/27752144
http://dx.doi.org/10.1038/srep35610

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