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Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity
The Wnt pathway plays a crucial role in self‐renewal and differentiation of cells in the adult gut. In the present study, we revealed the functional consequences of inhibition of canonical Wnt signaling in the intestinal epithelium. The study was based on generation of a novel transgenic mouse strai...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067622/ https://www.ncbi.nlm.nih.gov/pubmed/26864984 http://dx.doi.org/10.1002/dvg.22922 |