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Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation
The histone 3 lysine 9 methyltransferase Setdb1 is essential for both stem cell pluripotency and terminal differentiation of different cell types. To shed light on the roles of Setdb1 in these mutually exclusive processes, we used mouse skeletal myoblasts as a model of terminal differentiation. Ex v...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067623/ https://www.ncbi.nlm.nih.gov/pubmed/27790377 http://dx.doi.org/10.1038/celldisc.2016.37 |