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Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner

Apigenin (APG) is an edible plant-derived flavonoid that shows modest antitumor activities in vitro and in vivo. APG treatment results in cell growth arrest and apoptosis in various types of tumors by modulating several signaling pathways. In the present study, we evaluated interactions between APG...

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Detalles Bibliográficos
Autores principales: Chen, Minghui, Wang, Xueshi, Zha, Daolong, Cai, Fangfang, Zhang, Wenjing, He, Yan, Huang, Qilai, Zhuang, Hongqin, Hua, Zi-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067669/
https://www.ncbi.nlm.nih.gov/pubmed/27752089
http://dx.doi.org/10.1038/srep35468