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Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner
Apigenin (APG) is an edible plant-derived flavonoid that shows modest antitumor activities in vitro and in vivo. APG treatment results in cell growth arrest and apoptosis in various types of tumors by modulating several signaling pathways. In the present study, we evaluated interactions between APG...
Autores principales: | Chen, Minghui, Wang, Xueshi, Zha, Daolong, Cai, Fangfang, Zhang, Wenjing, He, Yan, Huang, Qilai, Zhuang, Hongqin, Hua, Zi-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067669/ https://www.ncbi.nlm.nih.gov/pubmed/27752089 http://dx.doi.org/10.1038/srep35468 |
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