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Increased collagen cross‐linking is a signature of dystrophin‐deficient muscle

INTRODUCTION: Collagen cross‐linking is a key parameter in extracellular matrix (ECM) maturation, turnover, and stiffness. We examined aspects of collagen cross‐linking in dystrophin‐deficient murine, canine, and human skeletal muscle. METHODS: DMD patient biopsies and samples from mdx mice and gold...

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Detalles Bibliográficos
Autores principales: Smith, Lucas R., Hammers, David W., Sweeney, H. Lee, Barton, Elisabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067682/
https://www.ncbi.nlm.nih.gov/pubmed/26616495
http://dx.doi.org/10.1002/mus.24998