A novel regulatory element (E77) isolated from CHO‐K1 genomic DNA enhances stable gene expression in Chinese hamster ovary cells

Vectors flanked by regulatory DNA elements have been used to generate stable cell lines with high productivity and transgene stability; however, regulatory elements in Chinese hamster ovary (CHO) cells, which are the most widely used mammalian cells in biopharmaceutical production, are still poorly...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Shin‐Young, Kim, Yeon‐Gu, Kang, Seunghee, Lee, Hong Weon, Lee, Eun Gyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067685/
https://www.ncbi.nlm.nih.gov/pubmed/26762773
http://dx.doi.org/10.1002/biot.201500464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067685/
https://www.ncbi.nlm.nih.gov/pubmed/26762773
http://dx.doi.org/10.1002/biot.201500464

Ejemplares similares