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F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE

The glycopeptide antibiotics are peptide-based natural products with impressive antibiotic function that derives from their unique three-dimensional structure. Biosynthesis of the glycopeptide antibiotics centres of the combination of peptide synthesis, mediated by a non-ribosomal peptide synthetase...

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Detalles Bibliográficos
Autores principales: Peschke, Madeleine, Brieke, Clara, Cryle, Max J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067714/
https://www.ncbi.nlm.nih.gov/pubmed/27752135
http://dx.doi.org/10.1038/srep35584