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Activated Factor X Induces Endothelial Cell Senescence Through IGFBP-5

Uncontrolled coagulation contributes to the pathophysiology of several chronic inflammatory diseases. In these conditions, senescent cells are often observed and is involved in the generation of inflammation. The coincidence of hyper-coagulation, cell senescence, and inflammation suggests the existe...

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Detalles Bibliográficos
Autores principales: Sanada, Fumihiro, Taniyama, Yoshiaki, Muratsu, Jun, Otsu, Rei, Iwabayashi, Masaaki, Carracedo, Miguel, Rakugi, Hiromi, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067718/
https://www.ncbi.nlm.nih.gov/pubmed/27752126
http://dx.doi.org/10.1038/srep35580