The "Goldilocks Effect" in Cystic Fibrosis: identification of a lung phenotype in the cftr knockout and heterozygous mouse

BACKGROUND: Cystic Fibrosis is a pleiotropic disease in humans with primary morbidity and mortality associated with a lung disease phenotype. However, knockout in the mouse of cftr, the gene whose mutant alleles are responsible for cystic fibrosis, has previously failed to produce a readily, quantif...

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Detalles Bibliográficos
Autores principales: Craig Cohen, J, Lundblad, Lennart KA, Bates, Jason HT, Levitzky, Michael, Larson, Janet E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC506778/
https://www.ncbi.nlm.nih.gov/pubmed/15279681
http://dx.doi.org/10.1186/1471-2156-5-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC506778/
https://www.ncbi.nlm.nih.gov/pubmed/15279681
http://dx.doi.org/10.1186/1471-2156-5-21

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