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Safety and efficacy of anti-PD-1 in patients with baseline cardiac, renal, or hepatic dysfunction
BACKGROUND: Anti-PD-1 therapy is increasingly used in various advanced malignancies. Patients with baseline organ dysfunction are largely excluded from clinical trials. Therefore it is unclear whether anti-PD-1 therapy is safe or effective in this setting. Further, these patients are often not candi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067899/ https://www.ncbi.nlm.nih.gov/pubmed/27777770 http://dx.doi.org/10.1186/s40425-016-0166-5 |