Anti-PD-1 increases the clonality and activity of tumor infiltrating antigen specific T cells induced by a potent immune therapy consisting of vaccine and metronomic cyclophosphamide

BACKGROUND: Future cancer immunotherapies will combine multiple treatments to generate functional immune responses to cancer antigens through synergistic, multi-modal mechanisms. In this study we explored the combination of three distinct immunotherapies: a class I restricted peptide-based cancer va...

Descripción completa

Detalles Bibliográficos
Autores principales: Weir, Genevieve M., Hrytsenko, Olga, Quinton, Tara, Berinstein, Neil L., Stanford, Marianne M., Mansour, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067905/
https://www.ncbi.nlm.nih.gov/pubmed/27777777
http://dx.doi.org/10.1186/s40425-016-0169-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067905/
https://www.ncbi.nlm.nih.gov/pubmed/27777777
http://dx.doi.org/10.1186/s40425-016-0169-2

Ejemplares similares