Activity of Pan-Class I Isoform PI3K/mTOR Inhibitor PF-05212384 in Combination with Crizotinib in Ovarian Cancer Xenografts and PDX()

The Phosphatidyl inositol-3 kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) and c-Met signaling pathways are often deregulated in cancer. The two pathways are interconnected and at least c-Met has been implicated in drug resistance. The aim of the study was to assess in ovarian cancer preclin...

Descripción completa

Detalles Bibliográficos
Autores principales: Iezzi, Alice, Caiola, Elisa, Broggini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067927/
https://www.ncbi.nlm.nih.gov/pubmed/27751351
http://dx.doi.org/10.1016/j.tranon.2016.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067927/
https://www.ncbi.nlm.nih.gov/pubmed/27751351
http://dx.doi.org/10.1016/j.tranon.2016.08.011

Ejemplares similares