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Tumor macrophages are pivotal constructors of tumor collagenous matrix

Tumor-associated macrophages (TAMs) promote tumor development, invasion, and dissemination by various mechanisms. In this study, using an orthotopic colorectal cancer (CRC) model, we found that monocyte-derived TAMs advance tumor development by the remodeling of its extracellular matrix (ECM) compos...

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Detalles Bibliográficos
Autores principales: Afik, Ran, Zigmond, Ehud, Vugman, Milena, Klepfish, Mordehay, Shimshoni, Elee, Pasmanik-Chor, Metsada, Shenoy, Anjana, Bassat, Elad, Halpern, Zamir, Geiger, Tamar, Sagi, Irit, Varol, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068227/
https://www.ncbi.nlm.nih.gov/pubmed/27697834
http://dx.doi.org/10.1084/jem.20151193