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Intra-molecular lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study

Covalently cross-linked advanced glycation end products (AGE) are among the major post-translational modifications to proteins as a result of non-enzymatic glycation. The formation of AGEs has been shown to have adverse effects on the properties of the collagenous tissue; they are even linked to a n...

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Detalles Bibliográficos
Autores principales: Collier, Thomas A., Nash, Anthony, Birch, Helen L., de Leeuw, Nora H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068345/
https://www.ncbi.nlm.nih.gov/pubmed/27648753
http://dx.doi.org/10.1016/j.bpc.2016.09.003