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Intra-molecular lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study
Covalently cross-linked advanced glycation end products (AGE) are among the major post-translational modifications to proteins as a result of non-enzymatic glycation. The formation of AGEs has been shown to have adverse effects on the properties of the collagenous tissue; they are even linked to a n...
Autores principales: | Collier, Thomas A., Nash, Anthony, Birch, Helen L., de Leeuw, Nora H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science B.V
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068345/ https://www.ncbi.nlm.nih.gov/pubmed/27648753 http://dx.doi.org/10.1016/j.bpc.2016.09.003 |
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