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Monte Carlo simulation of OLS and linear mixed model inference of phenotypic effects on gene expression

BACKGROUND: Self-contained tests estimate and test the association between a phenotype and mean expression level in a gene set defined a priori. Many self-contained gene set analysis methods have been developed but the performance of these methods for phenotypes that are continuous rather than discr...

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Detalles Bibliográficos
Autor principal: Walker, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068350/
https://www.ncbi.nlm.nih.gov/pubmed/27761350
http://dx.doi.org/10.7717/peerj.2575