Real-time colorimetric detection of DNA methylation of the PAX1 gene in cervical scrapings for cervical cancer screening with thiol-labeled PCR primers and gold nanoparticles

BACKGROUND: DNA methylation can induce carcinogenesis by silencing key tumor suppressor genes. Analysis of aberrant methylation of tumor suppressor genes can be used as a prognostic and predictive biomarker for cancer. In this study, we propose a colorimetric method for the detection of DNA methylat...

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Detalles Bibliográficos
Autores principales: Huang, Jin, Liou, Yu-Ligh, Kang, Ya-Nan, Tan, Zhi-Rong, Peng, Ming-Jing, Zhou, Hong-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068476/
https://www.ncbi.nlm.nih.gov/pubmed/27789946
http://dx.doi.org/10.2147/IJN.S116288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068476/
https://www.ncbi.nlm.nih.gov/pubmed/27789946
http://dx.doi.org/10.2147/IJN.S116288

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