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A double amino-acid change in the HLA-A peptide-binding groove is associated with response to psychotropic treatment in patients with schizophrenia

The choice of an efficient psychotropic treatment for patients with schizophrenia is a key issue to improve prognosis and quality of life and to decrease the related burden and costs. As for other complex disorders, response to drugs in schizophrenia is highly heterogeneous and the underlying molecu...

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Detalles Bibliográficos
Autores principales: Le Clerc, S, Taing, L, Fond, G, Meary, A, Llorca, P-M, Blanc, O, Beaune, P, Rajagopal, K, Jamain, S, Tamouza, R, Zagury, J-F, Leboyer, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068718/
https://www.ncbi.nlm.nih.gov/pubmed/26218850
http://dx.doi.org/10.1038/tp.2015.97