Intracellular Expression of PAI-1 Specific Aptamers Alters Breast Cancer Cell Migration, Invasion and Angiogenesis

Plasminogen activator inhibitor-1 (PAI-1) is elevated in various cancers, where it has been shown to effect cell migration and invasion and angiogenesis. While, PAI-1 is a secreted protein, its intercellular levels are increased in cancer cells. Consequently, intracellular PAI-1 could contribute to...

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Detalles Bibliográficos
Autores principales: Fortenberry, Yolanda M., Brandal, Stephanie M., Carpentier, Gilles, Hemani, Malvi, Pathak, Arvind P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068744/
https://www.ncbi.nlm.nih.gov/pubmed/27755560
http://dx.doi.org/10.1371/journal.pone.0164288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068744/
https://www.ncbi.nlm.nih.gov/pubmed/27755560
http://dx.doi.org/10.1371/journal.pone.0164288

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