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Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity

BACKGROUND: The lack of new anthelmintic agents is of growing concern because it affects human health and our food supply, as both livestock and plants are affected. Two principal factors contribute to this problem. First, nematode resistance to anthelmintic drugs is increasing worldwide and second,...

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Detalles Bibliográficos
Autores principales: Mathew, Mark D., Mathew, Neal D., Miller, Angela, Simpson, Mike, Au, Vinci, Garland, Stephanie, Gestin, Marie, Edgley, Mark L., Flibotte, Stephane, Balgi, Aruna, Chiang, Jennifer, Giaever, Guri, Dean, Pamela, Tung, Audrey, Roberge, Michel, Roskelley, Calvin, Forge, Tom, Nislow, Corey, Moerman, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068747/
https://www.ncbi.nlm.nih.gov/pubmed/27755544
http://dx.doi.org/10.1371/journal.pntd.0005058