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A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors

Alterations in central serotonin (5-hydroxytryptamine, 5-HT) neurotransmission and peripheral immune activation have been linked to multiple neuropsychiatric disorders, including depression, schizophrenia and autism. The antidepressant-sensitive 5-HT transporter (SERT, SLC6A4), a critical determinan...

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Detalles Bibliográficos
Autores principales: Baganz, N L, Lindler, K M, Zhu, C B, Smith, J T, Robson, M J, Iwamoto, H, Deneris, E S, Hewlett, W A, Blakely, R D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068761/
https://www.ncbi.nlm.nih.gov/pubmed/26529424
http://dx.doi.org/10.1038/tp.2015.168