Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain

Regulators of the histone H3-trimethyl lysine-4 (H3K4me3) mark are significantly associated with the genetic risk architecture of common neurodevelopmental disease, including schizophrenia and autism. Typical H3K4me3 is primarily localized in the form of sharp peaks, extending in neuronal chromatin...

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Detalles Bibliográficos
Autores principales: Dincer, A, Gavin, D P, Xu, K, Zhang, B, Dudley, J T, Schadt, E E, Akbarian, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068762/
https://www.ncbi.nlm.nih.gov/pubmed/26575220
http://dx.doi.org/10.1038/tp.2015.169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068762/
https://www.ncbi.nlm.nih.gov/pubmed/26575220
http://dx.doi.org/10.1038/tp.2015.169

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