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The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro

INTRODUCTION: Genome-Wide Association Studies have identified associations between lung function measures and Chronic Obstructive Pulmonary Disease (COPD) and chromosome region 6p21 containing the gene for the Advanced Glycation End Product Receptor (AGER, encoding RAGE). We aimed to (i) characteris...

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Detalles Bibliográficos
Autores principales: Miller, Suzanne, Henry, Amanda P., Hodge, Emily, Kheirallah, Alexander K., Billington, Charlotte K., Rimington, Tracy L., Bhaker, Sangita K., Obeidat, Ma’en, Melén, Erik, Merid, Simon K., Swan, Caroline, Gowland, Catherine, Nelson, Carl P., Stewart, Ceri E., Bolton, Charlotte E., Kilty, Iain, Malarstig, Anders, Parker, Stuart G., Moffatt, Miriam F., Wardlaw, Andrew J., Hall, Ian P., Sayers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068780/
https://www.ncbi.nlm.nih.gov/pubmed/27755550
http://dx.doi.org/10.1371/journal.pone.0164041