Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining

For more than half a century, genotoxic agents have been used to induce mutations in the genome of model organisms to establish genotype-phenotype relationships. While inaccurate replication across damaged bases can explain the formation of single nucleotide variants, it remained unknown how DNA dam...

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Detalles Bibliográficos
Autores principales: van Schendel, Robin, van Heteren, Jane, Welten, Richard, Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068794/
https://www.ncbi.nlm.nih.gov/pubmed/27755535
http://dx.doi.org/10.1371/journal.pgen.1006368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068794/
https://www.ncbi.nlm.nih.gov/pubmed/27755535
http://dx.doi.org/10.1371/journal.pgen.1006368

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