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Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson’s Disease

Understanding how genetic variation affects intermediate phenotypes, like DNA methylation or gene expression, and how these in turn vary with complex human disease provides valuable insight into disease etiology. However, intermediate phenotypes are typically tissue and developmental stage specific,...

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Detalles Bibliográficos
Autores principales: Rawlik, Konrad, Rowlatt, Amy, Tenesa, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068861/
https://www.ncbi.nlm.nih.gov/pubmed/27466229
http://dx.doi.org/10.1534/genetics.115.185967