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Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson’s Disease
Understanding how genetic variation affects intermediate phenotypes, like DNA methylation or gene expression, and how these in turn vary with complex human disease provides valuable insight into disease etiology. However, intermediate phenotypes are typically tissue and developmental stage specific,...
Autores principales: | Rawlik, Konrad, Rowlatt, Amy, Tenesa, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068861/ https://www.ncbi.nlm.nih.gov/pubmed/27466229 http://dx.doi.org/10.1534/genetics.115.185967 |
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