Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro

Major neuropsychiatric disorders are genetically complex but share overlapping etiology. Mice mutant for rare, highly penetrant risk variants can be useful in dissecting the molecular mechanisms involved. The gene disrupted in schizophrenia 1 (DISC1) has been associated with increased risk for neuro...

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Detalles Bibliográficos
Autores principales: Tropea, D, Molinos, I, Petit, E, Bellini, S, Nagakura, I, O'Tuathaigh, C, Schorova, L, Mitchell, K J, Waddington, J, Sur, M, Gill, M, Corvin, A P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068880/
https://www.ncbi.nlm.nih.gov/pubmed/26756905
http://dx.doi.org/10.1038/tp.2015.206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068880/
https://www.ncbi.nlm.nih.gov/pubmed/26756905
http://dx.doi.org/10.1038/tp.2015.206

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