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Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

Different neurodegenerative disorders often show similar lesions, such as the presence of amyloid plaques, TAU-neurotangles and synuclein inclusions. The genetically inherited forms are rare, so we wondered whether shared epigenetic aberrations, such as those affecting DNA methylation, might also ex...

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Detalles Bibliográficos
Autores principales: Sanchez-Mut, J V, Heyn, H, Vidal, E, Moran, S, Sayols, S, Delgado-Morales, R, Schultz, M D, Ansoleaga, B, Garcia-Esparcia, P, Pons-Espinal, M, de Lagran, M M, Dopazo, J, Rabano, A, Avila, J, Dierssen, M, Lott, I, Ferrer, I, Ecker, J R, Esteller, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068885/
https://www.ncbi.nlm.nih.gov/pubmed/26784972
http://dx.doi.org/10.1038/tp.2015.214