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Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns
Different neurodegenerative disorders often show similar lesions, such as the presence of amyloid plaques, TAU-neurotangles and synuclein inclusions. The genetically inherited forms are rare, so we wondered whether shared epigenetic aberrations, such as those affecting DNA methylation, might also ex...
Autores principales: | Sanchez-Mut, J V, Heyn, H, Vidal, E, Moran, S, Sayols, S, Delgado-Morales, R, Schultz, M D, Ansoleaga, B, Garcia-Esparcia, P, Pons-Espinal, M, de Lagran, M M, Dopazo, J, Rabano, A, Avila, J, Dierssen, M, Lott, I, Ferrer, I, Ecker, J R, Esteller, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068885/ https://www.ncbi.nlm.nih.gov/pubmed/26784972 http://dx.doi.org/10.1038/tp.2015.214 |
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