Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans

Individuals with type 2 diabetes display metabolic abnormalities, such as hyperglycemia, increased free fatty acids, insulin resistance, and altered ceramide levels, that contribute to vascular dysfunctions and compromised oxygen delivery. Caenorhabditis elegans fed a glucose-supplemented diet or wi...

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Detalles Bibliográficos
Autores principales: Ladage, Mary L., King, Skylar D., Burks, David J., Quan, Daniel L., Garcia, Anastacia M., Azad, Rajeev K., Padilla, Pamela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068937/
https://www.ncbi.nlm.nih.gov/pubmed/27507791
http://dx.doi.org/10.1534/g3.116.031583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068937/
https://www.ncbi.nlm.nih.gov/pubmed/27507791
http://dx.doi.org/10.1534/g3.116.031583

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