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Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion

Adoption of a streamlined version of the bacterial clustered regular interspersed short palindromic repeat (CRISPR)/Cas9 defense system has accelerated targeted genome engineering. The Streptococcus pyogenes Cas9 protein, directed by a simplified, CRISPR-like single-guide RNA, catalyzes a double-str...

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Detalles Bibliográficos
Autores principales: Ge, Daniel Tianfang, Tipping, Cindy, Brodsky, Michael H., Zamore, Phillip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068941/
https://www.ncbi.nlm.nih.gov/pubmed/27543296
http://dx.doi.org/10.1534/g3.116.032557