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YidC assists the stepwise and stochastic folding of membrane proteins

How chaperones, insertases and translocases facilitate insertion and folding of complex cytoplasmic proteins into cellular membranes is not fully understood. Here, we utilize single-molecule force spectroscopy to observe YidC, a transmembrane chaperone/insertase, sculpting the folding trajectory of...

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Detalles Bibliográficos
Autores principales: Serdiuk, Tetiana, Balasubramaniam, Dhandayuthapani, Sugihara, Junichi, Mari, Stefania A., Kaback, H. Ronald, Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069129/
https://www.ncbi.nlm.nih.gov/pubmed/27595331
http://dx.doi.org/10.1038/nchembio.2169