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YidC assists the stepwise and stochastic folding of membrane proteins
How chaperones, insertases and translocases facilitate insertion and folding of complex cytoplasmic proteins into cellular membranes is not fully understood. Here, we utilize single-molecule force spectroscopy to observe YidC, a transmembrane chaperone/insertase, sculpting the folding trajectory of...
Autores principales: | Serdiuk, Tetiana, Balasubramaniam, Dhandayuthapani, Sugihara, Junichi, Mari, Stefania A., Kaback, H. Ronald, Müller, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069129/ https://www.ncbi.nlm.nih.gov/pubmed/27595331 http://dx.doi.org/10.1038/nchembio.2169 |
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