Compounds that select against the tetracycline resistance efflux pump

We developed a competition-based screening strategy to identify compounds that invert the selective advantage of antibiotic resistance. Using our assay, we screened over 19,000 compounds for the ability to select against the TetA tetracycline resistance efflux pump in E. coli and identified two hits...

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Detalles Bibliográficos
Autores principales: Stone, Laura K., Baym, Michael, Lieberman, Tami D., Chait, Remy, Clardy, Jon, Kishony, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069154/
https://www.ncbi.nlm.nih.gov/pubmed/27642863
http://dx.doi.org/10.1038/nchembio.2176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069154/
https://www.ncbi.nlm.nih.gov/pubmed/27642863
http://dx.doi.org/10.1038/nchembio.2176

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