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Clinical study of a survivin long peptide vaccine (SurVaxM) in patients with recurrent malignant glioma

Survivin is an anti-apoptotic protein that is highly expressed in many cancers, including malignant gliomas. Preclinical studies established that the conjugated survivin peptide mimic SurVaxM (SVN53-67/M57-KLH) could stimulate an anti-tumor immune response against murine glioma in vivo, as well as h...

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Detalles Bibliográficos
Autores principales: Fenstermaker, Robert A., Ciesielski, Michael J., Qiu, Jingxin, Yang, Nuo, Frank, Cheryl L., Lee, Kelvin P., Mechtler, Laszlo R., Belal, Ahmed, Ahluwalia, Manmeet S., Hutson, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069322/
https://www.ncbi.nlm.nih.gov/pubmed/27576783
http://dx.doi.org/10.1007/s00262-016-1890-x