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Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of human islet cells from healthy and type 2 diabetic dono...

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Detalles Bibliográficos
Autores principales: Segerstolpe, Åsa, Palasantza, Athanasia, Eliasson, Pernilla, Andersson, Eva-Marie, Andréasson, Anne-Christine, Sun, Xiaoyan, Picelli, Simone, Sabirsh, Alan, Clausen, Maryam, Bjursell, Magnus K., Smith, David M., Kasper, Maria, Ämmälä, Carina, Sandberg, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069352/
https://www.ncbi.nlm.nih.gov/pubmed/27667667
http://dx.doi.org/10.1016/j.cmet.2016.08.020