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Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of human islet cells from healthy and type 2 diabetic dono...
Autores principales: | Segerstolpe, Åsa, Palasantza, Athanasia, Eliasson, Pernilla, Andersson, Eva-Marie, Andréasson, Anne-Christine, Sun, Xiaoyan, Picelli, Simone, Sabirsh, Alan, Clausen, Maryam, Bjursell, Magnus K., Smith, David M., Kasper, Maria, Ämmälä, Carina, Sandberg, Rickard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069352/ https://www.ncbi.nlm.nih.gov/pubmed/27667667 http://dx.doi.org/10.1016/j.cmet.2016.08.020 |
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