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Lipopolysaccharide Induces Human Pulmonary Micro-Vascular Endothelial Apoptosis via the YAP Signaling Pathway

Gram-negative bacterial lipopolysaccharide (LPS) induces a pathologic increase in lung vascular leakage under septic conditions. LPS-induced human pulmonary micro-vascular endothelial cell (HPMEC) apoptosis launches and aggravates micro-vascular hyper-permeability and acute lung injury (ALI). Previo...

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Detalles Bibliográficos
Autores principales: Yi, Lei, Huang, Xiaoqin, Guo, Feng, Zhou, Zengding, Chang, Mengling, Tang, Jiajun, Huan, Jingning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069405/
https://www.ncbi.nlm.nih.gov/pubmed/27807512
http://dx.doi.org/10.3389/fcimb.2016.00133