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Expression of Iron Regulatory Protein 1 Is Regulated not only by HIF-1 but also pCREB under Hypoxia

The inconsistent of responses of IRP1 and HIF-1 alpha to hypoxia and the similar tendencies in the changes of IRP1 and pCREB contents led us to hypothesize that pCREB might be involved in the regulation of IRP1 under hypoxia. Here, we investigated the role of pCREB in IRP1 expression in HepG2 cells...

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Detalles Bibliográficos
Autores principales: Luo, Qian-Qian, Qian, Zhong-Ming, Zhou, Yu-Fu, Zhang, Meng-Wan, Wang, Dang, Zhu, Li, Ke, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069441/
https://www.ncbi.nlm.nih.gov/pubmed/27766034
http://dx.doi.org/10.7150/ijbs.16437